Memory is a fundamental cognitive function of the human, and long-term memory (LTM) plays a substantial role in it. Despite all the research, the mechanism of the storage of LTM data in the brain, as well as the brain areas responsible for it, are not clearly identified yet. There is an ancient philosophical idea that the human memory is stored in an extracorporeal space, i.e. the human soul. In this study, using a materialistic approach, we aimed to take one step in investigating the role of human soul in brain functionality by assessing the compliance of this old idea with the available neuroscientific facts. Although with the current knowledge of the human it is not possible to accept nor to deny or examine the existence of soul, we think people in the fields of neuroscience, psychology, or psychiatry should start speaking about “human soul” in their works; belief in soul is nearly as old as the history of human, and one day people should start to scientifically investigate it.

long-term memory, human soul