Journal Cover
Volume 20 No 10 (2022)
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Involvement of dopaminergic receptors by sodium benzoate on memory, the electrical activity of CA1 pyramidal neurons and biochemical factors inParkinson-like male rats
Mohammad Mohammad Ali mansouri,Lotfolah Khajehpour , Zohreh Ghotbeddin and Ali shahriari
Abstract
Many people with Parkinson's disease (PD) experience mild memory loss and mental problems.
The main cause of cognitive problems is damage to areas involved in memory or thought-related
processes in the nervous system. Destruction of dopaminergic neurons in the Substantia Nigra Pars
Compacta is a major cause of Parkinson's disease and its symptoms. Considering the positive effects of
sodium benzoate on memory function, the present study aimed to investigate the possible involvement
of dopaminergic receptors in the positive effectsof this drug
Keywords
Dopamine receptors, Haloperidol, Memory impairment, Parkinson's disease, Rotenone
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