Volume 20 No 6 (2022)
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Levels of Cerebral Malaria Indices, Free radical Scavengers and Preventive Antioxidants in Plasmodiumberghei Infected Mice Treated with Phytochemical Extracts of Phyllanthus amarus Schum and Thonn
Opajobi AO , Onobrudu DA , Ojugbeli ET, Uzuegbu UE , Toloyai PY , Elu C , Oshiegbu W , Onyesom
Abstract
Cerebral malaria (CM) is one of the deadliest form of severe malaria, caused by prolonged oxidative stress and characterized by neurological dysfunctions. Antioxidant treatment in conjunction with antimalarials could provide an alternate chemotherapeutic pattern to curb oxidative stress associated with CM
Keywords
Anaemia, severe malaria, flavonoids, alkaloids, P. amarus, haematological indices
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