Volume 15 No 1 (2017)
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MULTI-PARTICULATE MESALAMINE USED IN THE MANAGEMENT OF IBD: A REVIEW
Meenakshi Jaiswal
Abstract
Crohn's disease and ulcerative colitis are examples of inflammatory bowel disease, which is a group
of diseases that cause persistent inflammation of the digestive tract. These illnesses are now major
public health concerns. With the development of targeted biologic therapies, the improvement of
older therapies like immunomodulators and 5-aminosalicylic acid, and a deeper understanding of
the mucosal immune system and the genetics involved in the pathogenesis of IBD, medical therapy
for IBD has advanced dramatically in the last decade. Inflammatory bowel disease treatment aims to
achieve and sustain remission. The standard practice in medicine nowadays is to start with less
intense treatments and work our way up to more intense ones if those fail or if the patient reports
that their illness is particularly aggressive. For this reason, multi-unit carriers are preferable over
single-unit ones. Pectin, among other biopolymers, stands out as a promising option for building
colon-specific carriers that are activated by microbes. In this article, we will discuss the current
methods of managing inflammatory bowel illness with multi particle medication delivery.
Keywords
Mesalamine, Multi-particulate, Management, and Inflammatory Bowel Disease
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