This study aimed to find range of third ventricle indices, their variation with age and gender in apparently normal subjects. The study was an observational and cross-sectional study of three years (between March 2017-March 2019 and June 2024 to August 2024) With the Institutional ethical committee clearance, soft copies of head CT scans of two hundred subjects (96 males and 104 females) were subjected to morphometric analysis of third ventricle’s height and width using dicom image software. Mean, standard deviation ranges were calculated. Two sample independent student t-test, Pearson’s correlation coefficient and Regression analysis were applied to find the gender variation. Comparing the mean level of 3rd ventricle height of two groups, Student’s t test showed significantly different and 11.2% higher height in males as compared to females (13.78 ± 2.80 vs. 15.52 ± 1.84, t=5.15, p<0.001).Similarly, Comparing the mean level of 3rd ventricle width of two groups, Student’s t test showed significantly different and 10.4% higher width in elderly females (above 50 years) as compared to males (3.23 ± 0.77 vs. 2.90 ± 0.42, t=3.78, p<0.001), may be attributed to some racial factors or the greater prevalence of the Alzheimer’s disease in elderly females.

Morphometric, Ventricle, Tomography, Computed, Comparatively