Volume 20 No 20 (2022)
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Multi Targeted DockingAnalysis and in Vitro Efficacy of Novel Substituted Piperidine-Flavone Analogues for Alzheimer’s Disease
K.Dhunmati,C.N. Nalini ,N.Ramalakshmi ,V.Niraimathi ,S.Amuthalakshm
Abstract
The prevalence of Alzheimer’s disease is increasing day to day. Till date there are very few FDA approveddrugs available used to treatAD. The multifactorial nature of the disease makes it very complicated for the treatment regimen, so in order to combat the prevalence of ADdevelopment of more drugswhich are capable of acting on multi targets are required.
Keywords
Piperidines, Alzheimer’s Disease, Flavones, Amyloid Peptide, MTT Assay,SHSY5Y Cell Line.
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