It is challenging to directly target neurological illnesses because of the complexity of the central nervous system, which is difficult to get around the brain's built-in defense mechanisms. The development of nanotechnology offers promising possibilities for overcoming this issue. Nano-engineered molecules can be made to pass the blood-brain barrier, target certain cells or signaling systems, react to endogenous cues, operate as vehicles for delivering genes, or act as a matrix to encourage axon extension and sustain cell survival. Nanotechnology is an emerging, interdisciplinary field of science and engineering with the potential to significantly alter how we manage and control materials and devices at the molecular level (often defined within the range of 1–100 nm), using physical or chemical approaches. We review existing regeneration treatments for neurological disorders, as well as nanotechnology's role as a nano-carrier and the technical, manufacturing, and regulatory difficulties that occur from the conception of nanoparticle-based regenerative treatments through their formulation. Additionally, it has been addressed what the objectives and targeted tactics for the various types of brain pathology are.

Neurological disorder, Nanoparticle, Blood brain barrier, Central nervous system