Targeted delivery has gained much attention in recent years among pharmaceutical industries and pharmacy researchers. Unlike normal drug delivery, tissue targeted drug delivery requires a special technology and techniques to manufacture the final product. In particular, delivering a drug to brain tissue poses various problems like penetration and availability of the drug on brain tissue is ever challenging. The drug delivery to the CNS is always challenging among researchers worldwide. Unlike other organ systems, the human brain architecture is so complex, and also various restrictions exist in the brain tissue inorder to access it. The concept of niosome loaded drug delivery system has gained much attention in recent years because of its high lipophilic nature and also it can easily attract lipophilic drugs and attract the brain tissue. Keeping the idea of explaining niosomes as a drug carrier for delivering drug candidates to the brain target, an attempt was made to review the niosome loaded drugs for Alzheimer’s Disease (AD) which is considered to be the most common neurological disorder. This review emphasises the drugs used for AD with their mechanism of actions and its characteristic features to get formulated with niosome with the formulation criteria. In addition to that, it emphasises the future perspective of niosome loaded drug delivery for the treatment of AD

10.14704/nq.2022.20.9.NQ44288