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Volume 20 No 12 (2022)
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OPTIMIZATION OF METHODS FOR ELIMINATING THE NEPHROTOXIC EFFECT OF ANTITUBERCULOSIS DRUGS IN PATIENTS WITH RESISTANT TUBERCULOSIS (LITERATURE REVIEW)
Aslonov Farrukh Ismoilovich, Usmonov Isomiddin Khaydarovich
Abstract
The review analyzes publications devoted to the frequency of renal adverse reactions during
tuberculosis chemotherapy. The most significantpathophysiological mechanisms causing development
of drug-induced nephrotoxicity are presented. The article describes the specific features ofnephrotoxic
effect of I line and II line of anti-tuberculosis drugs
Keywords
Multidrug resistant tuberculosis, acute kidney injury, anti-tuberculosis drugs, acute drug reactions, nephrotoxic side effects, adverse drug reactions, mycobacterium tuberculosis,molecular genetic methods
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