Anemia is one of the most common hematological complications found in children with HIV infection. The causes of anemia in patients with HIV are multifactorial including the duration of ARV administration, age at the time of ARV administration, administration of cotrimoxazole and Isoniazid drugs. The purpose of this study was to determine the relationship between the length of time receiving ARVs and the incidence of anemia in HIV-infected children at H. Adam Malik Hospital, Medan . The design of this study used observational analytic with retrospective cross-sectional method from medical records to determine the relationship between the length of ARV therapy and the incidence of anemia in HIV children at H Adam Malik Hospital as many as 32 samples were taken from medical records. The results showed that the moderate degree of anemia was 56.3 % , the severe degree was 28.1%, and the mild degree was 15.5%. Bivariate analysis There is a relationship between anemia and early age of ARV administration p value 0.0 44 , duration of ARV administration p value 0.0 13 , cotrimoxazole administration p value 0.0 29 . and administration of isoniazid p value 0.020 . Multivariate analysis found that the duration of ARV administration with p value 0.043, OR = 10,899 ( 95 % CI = 1.073- 110.668 ) was the most influential risk factor in influencing the onset of anemia, which means the longer the administration ARV drugs , the greater the incidence of anemia . There is a relationship between the initial age of ARV administration, duration of ARV administration, administration of cotrimoxazole and isoniazid on the incidence of anemia in HIV-infected children.

Anemia, HIV, Children, ARV, cotrimoxazole, Isoniazid