In terms of global mortality and morbidity, chronic kidney disease ranks first among equals. Despite recent advances in our knowledge of disease processes, conventional methods of treatment have proven unable to halt the spread of most chronic conditions. Research efforts are concentrated on pinpointing the precise mechanisms at play so that more potent therapy alternatives might be discovered. Many renal disease processes are regulated by prostaglandin E2 via its four EP receptors; as a result, EP receptors may become useful therapeutic targets for nephrotic syndrome and other kidney diseases. The kidney contains a very variable distribution of PGs, synthases, and receptors.

Kidney diseases, Receptors, Diabetes, Hypertension, Nephropathy