Volume 20 No 9 (2022)
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Performance Analysis of Multiple Sequence Alignment Algorithm using Swarm Intelligence
Karamjeet Kaur, Anil Kumar Sagar, Sudeshna Chakraborty and Manoj Kumar Gupta
Abstract
Biological data sequencing is a complicated operation because of the nature of the data. Every living
organism's DNA, RNA, and proteins can benefit greatly from the sequence alignment strategy. Accurate
and fast alignment helps to find common evolutionary and structural relationship which in turn helps to
design drugs. Even after years of using the sequence alignment approach, each algorithm produces a
different solution for the same alignment problem. An additional issue with sequence alignment is that
the algorithms and data it uses are computationally complex. Protein and DNA alignments can take days
to analyze in some circumstances. Control of various sequence alignment scores is enhanced by several
stochastic approaches. Multiple sequence alignment improves the quality and this task is made easier by
the swarm intelligence method. An investigation on swarm intelligence-based methods for analyzing
multiple sequence alignment is presented here. MATLAB software and a well-known protein dataset are
used in the research procedure, which assesses the algorithm's time complexity and scoring.
Keywords
Multiple Sequence Alignment, Particle Swarm Optimization, DNA, RNA and Swarm Intelligence
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