Volume 20 No 22 (2022)
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Pharmacognostical & Phytochemical Potential of Matricaria chamomilla Linn Flowers
Umesh Chandra Pandey, Dr. Karunakar Shukla, Dr. Mohit Chaturvedi
Globally distributed, Matricaria chamomilla L (M. chamomilla, Asteraceae) is a well-known medicinal plant. In traditional medicine, it is commonly used to treat a wide range of illnesses, such as infections, liver disorders, gastrointestinal, respiratory, and neuropsychiatric conditions. Additionally, it has antibacterial, antiemetic, sedative, and antispasmodic properties. This study looked into the pharmacognostical characteristics, phytochemical makeup, and anxiolytic potential of M. chamomilla flower extracts made from alcohol. The various pharmacognostical factors were assessed using modified versions of established methods. The well-established test technique that is documented in the literature was used to determine the qualitative analysis of different phytochemical elements. The hole board, open field test, and elevated plus maze models were used to assess the anxiolytic activity. The standard anxiolytic medication diazepam (1 mg/kg) and the extract (250, 500, and 750 mg/kg) were tested for efficacy. Alcoholic extract was subjected to phytochemical examination, which identified the presence of proteins, carbohydrates, flavonoids, and glycosides. Animals given extract had exploratory behavior that was comparable to benzodiazepines in every test. The elevated plus maze apparatus's number of entries and duration of time spent in the open arm were both considerably increased by the extract, according to the findings. The extract significantly increased the frequency of square crosses, assisted rearings, and rearings in the open field test—all indicators of exploratory activity. All things considered, these findings point to the possibility that the alcoholic extract of M. chamomilla flowers has anxiolytic properties and support the traditional belief.
Anxiolytic, Matricaria chamomilla L, Elevated plus maze, Open field test, Hole board models.
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