In addition to offering a wide variety of pharmaceuticals, nature may also have the solutions to any medical problems. There are still many clinically useful medicines found in nature. Ulcer diseases are a significant and expanding category of health problems. Today, a variety of drugs are used to treat peptic ulcers, but all of them have drawbacks, such as the potential for relapse and drug combinations. Peptic ulcers are a condition that is increasingly being treated with plant-based medications. Pure phytochemicals are difficult to get as ulcer treatments. Both time and money are invested in it. Mangifera indica, Azadirachta indica, Ocimum sanctum, Annona squamosa, Mimosa pudica, Terminalia chebula, Ficus religiosa, Carica papaya, Aegle marmelos, Moringa oleifera, Psidium guajava, and other plants are some of the plants that act as antiulcer herbals and are ignored for their beneficial function. Flavonoids can help to decrease free radicals to some extent in combating ulcers. Numerous isolated compounds have significant anti-ulcer activity, such as mangiferin, nimbidin, eugenol, tannic acid, mimosine, gallic acid, chebulinic acid, naringenin, papain, and others. The results of this review paper suggest that the anti-ulcer effect is mediated by a number of medicinal plants and their chemical components. This drives us towards development of novel phytoconstituents with structural modification to act as better antiulcer drug molecules at clinical level

Anti-Ulcer, Peptic Ulcer, Phyto constituents, Structural Modification