Differentiating typical Parkinson Disease from atypical parkinsonian illnesses (APDs), predominantly in the primary phases, is one of the common diagnostic and clinical difficulties in the early & effective management of these disorders which is crucial for long-term prognosis, and quality of life of the patient. They can be distinguished using clinical measures and conventional magnetic resonance sequences. Diffusion tensor imaging (DTI), Diffusion-weighted imaging (DWI), susceptibility weighted images are some advanced MRI techniques that possibly could be helpful in the identification of various spectrum of Parkinsonian disorders, according to the recent studies & reports.

I.PS, APD, MRI, DTI, DWI, Parkinson disease, PSP.