Volume 21 No 6 (2023)
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ROLE OF miRNA IN THE DIAGNOSIS AND PROGRESSION OF BREAST CANCER AMONG YOUNG AGE FEMALE POPULATION
DR MUHAMMAD SHAHERYAR BHATTI, DR ZUNAIRA SADIQ, DR AYESHA RAZZAQ
Abstract
Introduction: Breast cancer remains a formidable health challenge worldwide, impacting both the older and younger female populations. Objectives: The main objective of the study is to find the role of miRNA in breast cancer detection at young age female population. Material and methods: This study employed a retrospective cohort design to investigate the role of miRNA in the diagnosis and progression of breast cancer among young age female populations. Clinical and pathological data were collected from medical records, including patient demographics, tumor characteristics, histological subtypes, and disease stage. Blood samples were collected from each participant to extract miRNA for subsequent analysis. Results: In the study investigating the role of miRNA-let-7 in the diagnosis and progression of breast cancer among young age female populations, a cohort of 120 participants aged 20 to 40 years was enrolled. Clinical and pathological characteristics were documented, and blood samples were collected for miRNA analysis. The participants' age distribution ranged from 20 to 40 years, with an average age of 32.5 years. Conclusion: It is concluded that this study underscores the significance of miRNA-let-7 in breast cancer diagnosis and progression among young women. The observed downregulation and its correlation with disease severity suggest its potential utility as a diagnostic and prognostic biomarker.
Keywords
Breast cancer remains a formidable health challenge worldwide, impacting both the older and younger female populations.
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