The usage of indigenous medicinal plants for novel drug discovery and as alternate therapeutics has been trending since the past few decades. Tinospora cordifolia, popularly called as Amruta, Guduchi or Giloya, is a therapeutic climber chiefly found in the Indian subcontinent. It belongs to the Menispermaceae family and has been widely used over the ages in Indian Ayurveda and folk medicine. A wide range of bioactive compounds from the categories of alkaloids, steroids, sesquiterpenoids, diterpenoids, phenolics, aliphatic compounds and polysaccharides etc. have been isolated from the plant making it an immensely popular choice among researchers. This resulted in the identification of a large number of pharmacological attributes of the plant including antioxidative, immunomodulatory, hepatoprotective, neuroprotective, hypoglycemic, and anticancer activity etc., making it a very important commercially important plant as well. In the present review, the therapeutic activities of Guduchi plant and its derivatives are discussed in relevance to their biological actions

Guduchi, Tinospora cordifolia,Giloya, Amruta, Ayurveda, pharmacological activity, bioactive compounds, immunomodulation.