Volume 20 No 13 (2022)
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Relationship Between Toxoplasmosis Infection and Levels of Progesterone and Estrogen Hormones in Aborted Women In Wasit Province, Iraq
hifaa Ali Abdulmohsin Al-Hachami , May Naji Al-Khanak , Jalal AbdulRazzaq Tofah Al-Azzawi
Abstract
The current study aimed to determine relationship between Toxoplasma gondii infection and levels of
Progesterone and Estrogen in aborted women and normal delivery women in Wasit province. The study
included two main groups: patients and controls of Iraqi women. The control was included 50 women
(non-infected normal delivery women), whilst the patient group were included 146 Toxo-seropositive
serum samples. Serum samples from patients and control were collected and detected the levels of
Progesterone and Estrogen by using ELISA technique. The results also showed the total rate of
Progesterone in 1st trimester, 2nd trimester and 3rd trimester were 146/300 (4.50 ± 1.77, 7.72 ± 4.19 and
30.46 ± 11.93) ng/ml, respectively in T. gondii seropositive patients serum samples, whereas 50/50
(21.69 ± 7.89, 41.63 ± 15.56 and 126.72 ± 39.71) respectively. In control serum samples by using ELISA,
statistical analysis results indicated high significant differences between the patients and control
women. Also, the results showed the total rate of Estrogen in 1st trimester, 2nd trimester and 3rd
trimester were 146/300 (91.41 ± 65.80, 853.19 ± 331.40 and 1003.18 ± 530.02) ng/ml, respectively in
T. gondii seropositive patients serum samples, whereas 50/50 (1042.86 ± 501.69, 4327.09 ± 1294.66
and 4972.67 ± 1010.16) respectively. In control serum samples by using ELISA, statistical analysis
results indicated high significant differences between patients and control women.
Keywords
Toxoplasmosis, ELISA, Progesterone, Estrogen
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