


Volume 20 No 17 (2022)
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Repurposing Existing Drugs To Find Novel Therapies For Alzheimer’s Disease
Abhishek Dudhal, K.Gowri, Dr. V.Chitra
Abstract
The goal of this review is to determine whether it is feasible to treat Alzheimer's disease with already available drugs for other diseases. Alzheimer's disease is a neurological condition that worsens over time and causes memory loss, cognitive decline, and ultimately death. Alzheimer's disease presently has no known cure and the medicines that are available only partially alleviate symptoms. There is an urgent need to find novel therapy modalities because there are few effective treatments for Alzheimer's disease. Given the similarities between Anti-cancer, phosphodiesterase inhibitors, calcium channel blockers, , insulin glucagon-like peptide-1 (GLP-1) receptor agonists, mood stabilizers, antivirals, non-steroidal anti-inflammatory drugs, antibiotics, and antioxidants for Alzheimer's disease, it is theorized that current anticancer and above mentioned drug candidates might be used to treat Alzheimer's disease.
Keywords
Alzheimer’s disease, Anti-cancer, calcium channel blockers, phosphodiesterase inhibitors, insulin glucagon-like peptide-1 (GLP-1) receptor agonists, mood stabilizers, antivirals, non-steroidal anti-inflammatory drugs, antibiotics, antioxidants, clinical trials.
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