Journal Cover
Volume 17 No 7 (2019)
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Research Progress of MicroRNA in Spinal Cord Injury
Yu-Bao Lu, Zong-Yan Cai, Ge-Ge He, Jia-Yu Zhao, Yu-Tong Chen, Shi-Min Zheng, Xue-wen Kang
Abstract
Spinal cord injury (SCI) is a central nervous system disease with severe damage that causes partial or complete loss
of movement and sensation below the injury segment, causing dysfunction. MicroRNAs (miRNAs) are a class of noncoding single-stranded RNA small molecules of approximately 18-25 nucleotides in length. Studies have shown that
miRNAs play a regulatory role in the pathological process of spinal cord injury, which will provide a new target for the
treatment of SCI. This article reviews the expression changes of microRNAs after spinal cord injury and the possible
mechanisms of action in pathological processes.
Keywords
microRNA, spinal cord injury, regulation
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