Sulfur-containing heterocycles are a class of organic compounds that play a vital role in various biological processes and have garnered significant attention in both synthetic chemistry and pharmaceutical research. This review provides a comprehensive overview of the synthesis methodologies employed to access diverse sulfur-containing heterocycles and explores their wide-ranging applications in the field of biology. The first section of this review focuses on the various synthetic approaches utilized for the construction of these heterocyclic motifs. It delves into classical methods as well as recent advancements in the field, highlighting the strategic use of sulfur-containing building blocks and their incorporation into complex molecular structures. In the subsequent sections, we delve into the diverse applications of these biologically significant sulfur-containing heterocycles. Their pivotal roles as pharmacophores in drug design and development are examined, emphasizing their interactions with biological targets and potential therapeutic effects. Additionally, their significance in agrochemicals, materials science, and other industrial applications is discussed, showcasing the versatility of these compounds beyond medicinal chemistry. this review highlights the biological activities exhibited by certain sulfur-containing heterocycles. It explores their potential as antimicrobial agents, antiviral compounds, anticancer therapeutics, and more. Insights into structure-activity relationships and mechanistic studies are also presented to shed light on their mode of action.

Sulfur-containing heterocycles are a class of organic compounds that play a vital role in various biological processes