In the current study, we wanted to evaluate Gardenia resinifera potential to prevent obesity in Triton X-100 induced rats. The efficiency of the common anti-obesity drug atorvastasin (10 mg/kg b.wt.) was compared to that of the methanolic extract of Gardenia resinifera (MEGR), which was synthesized and tested at different doses (50 mg/kg, 100 mg/kg,). The serum levels of total cholesterol (TC), triglycerides (TG), low-density lipoproteins (LDL), and very low-density lipoproteins (VLDL) all significantly (P 0.05) dropped when MEGR was administered along with Triton X-100, but high-density lipoproteins (HDL) rise. We demonstrate that MEGR has potential anti-obesity activity based on our findings.

Gardenia resinifera, Triton X-100, lipid level, methnolic extract, obesity