Background: Anterior cervical discectomy and fusion procedures are one of the most common procedures performed in spinal surgery. Anterior cervical discectomy and fusion (ACDF) is the current gold standard for managing symptomatic anterior cervical degenerative disc disease. Present study was intended to assess the functional and radiological outcome of anterior cervical discectomy and fusion, its technical difficulties and outcome. Material and Methods: Present study was a prospective longitudinal observational, hospital based study., conducted in patients of age 20 years and above of both sexes, with Cervical prolapsed intervertebral disc, Infective cervical spondylodiscitis, Cervical myelopathy, Cervical myelomalacia, underwent anterior cervical discectomy and fusion. Results: The mean age among the distribution of cases was 50.02 ±12.32 years. Males (80.39 %) were the most affected. Maximum numbers of patients were having PID (56.86%), followed by CSM (39.22%), KOCHS (1.96%) and Myelomalacia (1.96%). The maximum numbers of patients spine affected was C5-6 level (68.62%), followed by C4-5 level (31.37%), C6-7 (27.45%) and C3-4 level (3.92%). The majority of patients presented with motor deficiency (98.04%), followed by sensory deficiency (92.15%), reflexes (39.21%), gait (33.33%) and bowel/bladder involvement (1.96%). The patients radiological feature preoperatively had reduced disc space (66.67%), followed by presence of osteophytes (64.71%), alignment not proper (29.41%) and stability hampered (7.84%). The comparison of pre and post-operative clinical manifestations among patients showed that there was statistically significant improvement in sensory and motor deficiency post operatively. (P<0.005). The comparison of pre and post-operative radiological manifestations among patients showed that there was statistically significant improvement in alignment and osteophytes decreased post operatively. (P<0.005). Conclusion: Anterior cervical discectomy and fusion is an excellent method in terms of effectiveness and safety, and with better results.

Anterior cervical discectomy and fusion, prolapsed intervertebral disc, Infective cervical spondylodiscitis, Cervical myelopathy, Cervical myelomalacia