Biological organisms react to environmental stimuli and adjust to changing situations. For the past two decades, polymer researchers have been attempting to emulate this behavior by developing so-called smart polymers. Polymers that exhibit reversible large, physical or chemical modifications in relation to tiny exterior variations in environmental variables, including heat, pH, sunlight, magnetic or electrical field, ionic variables, biomolecules, and so on, are classified as this.Smart polymers have emerged as a crucial category of polymers, with their applications expanding rapidly. The topic has grown rapidly during the last two to three centuries. Smart polymers have been employed in biotechnology, medicine, and engineering. They are also known as stimuli-responsive soluble-insoluble polymers or environmentally sensitive polymers. Smart polymers offer extremely potential biomedical applications as medicinal substance delivery methods, tissue engineering scaffolds, cell culture scaffolds, bioseparation tools, sensors, or actuator structures. The current research aims to reviewsmart polymers, as well as their most innovative and significant uses as biomaterials in tissue engineering and drug delivery. Due of their significant prospective in the biomedical area, dual-stimuli-responsive substances will also be demonstrated.Despite the fact that there have been a lot of studies published in this field recently, the current review focuses on the advancements of smart polymers in the past decade with particular industrial fields.

Smart polymer, biomedical applications, environmental stimuli, medicinal substance delivery methods