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Volume 20 No 7 (2022)
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Synthesis and antimicrobial potential of novel polyphenolic dendrimers
Raman Kalia, Balvinder Singh, Surya Prakash Gautam and Suresh Kumar
Abstract
In the present work, eleven dendrimeric compounds (11-21) were synthesized by Michael addition
reaction to avoid the structural defects at higher generations by using large excess of Michael donor
(EDA). The synthesized compounds were characterized by IR, NMR and Mass Spectroscopy. Progress of
the chemical reactions and the purity level of the compounds was evaluated using TLC plates. The
biological studies of synthesized dendrimers – (11-21) were carried out for anti-bacterial and anti-fungal
activities
Keywords
Michael addition, TLC plates, anti-bacterial, anti-fungal and Griseofulvin.
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