Current wound care has undergone a very rapid development, although there are still many uses of honey as wound care because it is considered economical. Increased field of science and technology contributes to the practice of wound care. The purpose of this study was to analyze the effect of high blood sugar on wound healing and comparison of effectiveness of wound care using modern wound care at General Hospital and treatment using honey at Private Hospital by using quantitative approach with quasi experimental research. The sample was DM patients with gangrenous lesions treated for 15 days with 5 times wound care using a wound assessment measurement. A total of 20 respondents were selected with control group 10 respondents using modern care and another 10 respondents using honey. The independent variable is wound care and the dependent variable is the high blood sugar. The analysis used frequency, percentage, chi square test, and onewayanova. The results showed no relationship between high blood sugar with wound healing p = 0.943> 0.05. There was a significantdifferences between modern wound care and using honey in seven out of ten assessments, i.e., wound edges, cave, exudate type, skin color, edema tissue, granulation tissue, and epithelialization (p = 0.000 < 0.05). This suggests that modern wound care is more effective than wound care using honey

Blood pressure, conventional care, modern care, wound assessment