Background: Multiple sclerosis has a high burden of care on the patient and their family, which can affect the spiritual well-being of the family. Therefore, this study was conducted to determine the relationship between spiritual well-being and the burden of care in family caregivers of patients with multiple sclerosis. Methods: In this cross-sectional study, 100 family caregivers of patients with MS referred to the MS Society of Hamadan, Iran, in 2020 were selected using the convenience sampling method. The data gathering tools were Paloutzian and Ellison’s Spiritual Well Being Scale, the Zarit Burden Interview, and Expanded Disability Status Scale. Data were analyzed using descriptive/analytical statistics and SPSS software version 16. Results: The mean scores of spiritual well-being and family caregiver burden were 93.50±16.84 and 25.50±16.24, respectively. Based on the Pearson correlation coefficient, there was a significant inverse relationship between spiritual well-being and care giving burden (p= 0.001, r=-0.48). The multiple regression test results showed that the spiritual well-being variable significantly predicts the burden of care (p=0.0001, β=-0.311). Conclusion: In this study, spiritual well-being had a significant and inverse correlation with the burden of care. Therefore, it is emphasized to consider the spiritual well-being of family caregivers to reduce the consequences of care burden.

Spirituality, Care Burden, Multiple Sclerosis, Cross-Sectional Study