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Volume 20 No 9 (2022)
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The role of sST2 as biochemical markers for cardiac fibrosis in patients with Myocardial Infarction
Mahmoud Hassan Ali, Dr. Shaymaa Z.Nada, Dr. Lamya A.Darwish
Abstract
In Iraq, ischemic heart disease ranks first among the top ten killers with a mortality rate of 11.2 percent,
and it ranks fourth among the top ten causes of hospitalization with a 5.35 percent rate in 2020. A
myocardial infarction (MI) happens when blood flow to the heart's coronary artery is reduced or
interrupted, harming the heart muscle. When the heart needs more blood flow—during activity or
excitement—this situation tends to happen more frequently. is a widespread occurrence in Iraq and the
world's greatest cause of mortality.The Suppression of Tumorigenicity 2 protein (ST2) is a member of
the interleukin (IL) 1 receptor family with transmembrane (ST2L) and soluble (sST2) isoforms that are
expressed in several cells in different conditions and following various triggers (e.g. inflammation,
stress).
Keywords
Suppression of Tumorigenicity 2, sST2, myocardial infarction
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