Corona virus 2019 could be a pandemic with no specific therapeutic agent and substantial mortality. it's critical to search out new treatment to work out whether convalescent plasma transfusion beneficial within the treatment of critically ill patient with severe acute respiratory syndrome. Administration of convalescent plasma containing neutralizing antibody was followed by improve in their clinical status1 we still don't have drug or vaccines that specially target this vile virus. Hence, the requirement to seek out alternative therapeutic option is to optimize recovery and reduce the viral load because of COVID- 19 .Convalescent plasma therapy may be a potential therapeutic option being explored all over the globe. in this study, that mentioned the utilization of plasma therapy2. The plasma collected from convalescent COVID-19 patients contains neutralizing antibodies which show potential benefit in reducing viral load ...improvement in clinical symptoms like fever, cough and Dyspnoea. Lack of huge scale clinical trials on plasma therapy may be a major shortcoming before this therapeutic modality starts being extensively used.

Plasma therapy, COVID-19 & Plasma therapy, History of plasma therapy