Volume 20 No 13 (2022)
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To determine the biochemical and hematological differences between diabetic patients and non-diabetic controls of asymptomatic bacteriuria in and around Indore region
M. Deepthi, Rohit Gupta Kailash Jatav
Abstract
Background: A clear knowledge of the causative agents of UTIs and antibiotic susceptibility pattern of the isolates would be helpful in the treatment of UTIs. Data generated from this study could provide useful information for the effective management of diabetes mellitus and the prevention chronic complications. Hence, the aim of the present study is to establish biochemical and hematological differences between diabetic patients and non-diabetic controls of asymptomatic bacteriuria (ASB). Materials & Methods: This research was conducted at the Index Medical College and Hospital after receiving approval from the Institutional Ethics Committee. The majority of patients with diabetes are seen at the hospital's diabetic clinics, which are extremely well-established and run very smoothly. Patients come here for routine checks and treatment. Informed consent or assent, in addition to completion of a questionnaire, and ethical approval are all necessities. Results: Patients with diabetes had significantly higher levels of serum creatinine, C-reactive protein (CRP), and fasting plasma glucose (FPG) compared to non-diabetic controls (P < 0.05). Conclusion: There was no discernible difference between the patterns of resistance of isolates taken from diabetic patients and those obtained from controls who did not have diabetes in terms of the resistance patterns. This suggests that the rates of exposure to antimicrobial compounds experienced by bacteria from these two habitats are comparable to one another.
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