Volume 20 No 13 (2022)
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FORMULATION, DEVELOPMENT & CHARACTERIZATION OF SHOREA ROBUSTA RESIN AND CARTHAMUS TINCTORIUS OIL
Shrikant Mahadev Darekar, S. Jayakumari
Abstract
The formulation, development, and characterization of Shorea robusta resin and
Carthamus tinctorius oil are the primary objectives of the current work.
METHODS: 100 g of Shorea robusta resin powder was methodically extracted in a Soxhlet method with
200 ml of ethanol. The extract was thoroughly dried in a rotary evaporator at 40 °C (yielding 68.0 g), and
then it was kept at room temperature for usage. To identify different phytoconstituents, ethanolic extracts
underwent a variety of qualitative chemical assays. Tween 80 and polyethylene glycol (PEG) were used
in a 3:1 ratio to create a nano-emulsion without the use of any drugs. 3ml of tween 80 and 1ml of PEG
were combined in this. 10% of the formulation ratio i.e. 1ml, of Carthamus tinctorius oil, was added. The
3:1:1 ratio of tween 80, PEG, and CTO solution was mixed with the help of a magnetic stirrer rotating at
500 rpm, and continuous stirring was done until the emulsion was created. For the parameters of
appearance, odor, color, homogeneity, pH, and spreadability, all the produced ointments were evaluated.
RESULTS- The physical appearance, color, smoothness, separation of phase, homogenization, and initial
skin sensation of the ointment compositions are all examples of organoleptic qualities. All of the
formulations' viscosities were measured and found to range between 2345.33 3.06 and 2396.33 10.69
CPS at 10 rpm.
CONCLUSION- The gelling polymer formulation using Shorea robusta resin and Carthamus tinctorius oil
was determined to be more promising than other formulations since it exhibits noticeably better
physicochemical properties
Keywords
Shorea robusta, Resin, Carthamus tinctorius oil, Characterization
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