Volume 20 No 13 (2022)
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FORMULATION, DEVELOPMENT & CHARACTERIZATION OF SHOREA ROBUSTA RESIN AND CARTHAMUS TINCTORIUS OIL
Shrikant Mahadev Darekar, S. Jayakumari
Abstract
The formulation, development, and characterization of Shorea robusta resin and Carthamus tinctorius oil are the primary objectives of the current work. METHODS: 100 g of Shorea robusta resin powder was methodically extracted in a Soxhlet method with 200 ml of ethanol. The extract was thoroughly dried in a rotary evaporator at 40 °C (yielding 68.0 g), and then it was kept at room temperature for usage. To identify different phytoconstituents, ethanolic extracts underwent a variety of qualitative chemical assays. Tween 80 and polyethylene glycol (PEG) were used in a 3:1 ratio to create a nano-emulsion without the use of any drugs. 3ml of tween 80 and 1ml of PEG were combined in this. 10% of the formulation ratio i.e. 1ml, of Carthamus tinctorius oil, was added. The 3:1:1 ratio of tween 80, PEG, and CTO solution was mixed with the help of a magnetic stirrer rotating at 500 rpm, and continuous stirring was done until the emulsion was created. For the parameters of appearance, odor, color, homogeneity, pH, and spreadability, all the produced ointments were evaluated. RESULTS- The physical appearance, color, smoothness, separation of phase, homogenization, and initial skin sensation of the ointment compositions are all examples of organoleptic qualities. All of the formulations' viscosities were measured and found to range between 2345.33 3.06 and 2396.33 10.69 CPS at 10 rpm. CONCLUSION- The gelling polymer formulation using Shorea robusta resin and Carthamus tinctorius oil was determined to be more promising than other formulations since it exhibits noticeably better physicochemical properties
Keywords
Shorea robusta, Resin, Carthamus tinctorius oil, Characterization
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